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CD81 is a 26 kD non-glycosylated member of the tetraspanin superfamily (TM4SF). CD81 is expressed on T and B cells, NK cells, monocytes, dendritic cells, thymocytes, endothelial cells, and fibroblasts. It also has low levels of expression on granulocytes. CD81 induces B cell adhesion via VLA-4 integrin and has been shown to play a role in early T cell development. CD81 associates with several other cell-surface proteins in a multimolecular complex, including CD19, CD21, CD20, CD37, CD53, and CD82 in B cells, and CD4, CD8, and CD82 in T cells. CD81 is frequently expressed on exosome membranes used to characterize exosome populations from a variety of body fluids.

This antibody is quality control tested on exosomes by ELISA and flow cytometry.

Size               50μg,  100μg

Clonality           Mouse Monoclonal Unconjugated

Reactivity          Human

Concentration       0.5mg/ml

Applification        FACS, IF, ELISA